Acetonitrile → 5-Benzyloxy-1-isopropyl-1H-indole-2-carboxylic acid ethyl ester

HRID 814798Notes

Reaction equation

HRID 814798 reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[nH:7][c:8]2[cH:9][cH:10][c:11]([O:15][CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[cH:12][c:13]2[cH:14]1.[CH3:37][C:38]#[N:39].[CH:29]([CH3:30])([CH3:31])[CH2:32][S:33]([O-:34])(=[O:35])=[O:36].[Cs+:27].[Cs+:28]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[n:7]([CH:29]([CH3:30])[CH3:31])[c:8]2[cH:9][cH:10][c:11]([O:15][CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[cH:12][c:13]2[cH:14]1

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 95721Ethyl 5-(phenylmethoxy)-1H-indole-2-carboxylateHCID 104967Cesium cation2×HCID 22141912Isopropyl-methanesulfonate

Product 1

HCID 670735335-Benzyloxy-1-isopropyl-1H-indole-2-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-45b7a45fd2da43678f3ed7c6295e9dfb
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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