2-Aminopyrimidine-5-boronic acid, pinacol ester → 5-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)pyrimidin-2-amine

HRID 814868Notes

Reaction equation

HRID 814868 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([cH:23][cH:24]1)-[c:6]1[n:7][c:8](-[c:14]3[n:15]([CH:20]([CH3:21])[CH3:22])[n:16][c:17]([CH3:19])[n:18]3)[cH:9][n:10]1[CH2:11][CH2:12][O:13]2.[CH3:25][C:26]1([CH3:27])[C:28]([CH3:29])([CH3:30])[O:31][B:32]([c:33]2[cH:34][n:35][c:36]([NH2:39])[n:37][cH:38]2)[O:40]1>>[c:2]1(-[c:33]2[cH:34][n:35][c:36]([NH2:39])[n:37][cH:38]2)[cH:3][c:4]2[c:5]([cH:23][cH:24]1)-[c:6]1[n:7][c:8](-[c:14]3[n:15]([CH:20]([CH3:21])[CH3:22])[n:16][c:17]([CH3:19])[n:18]3)[cH:9][n:10]1[CH2:11][CH2:12][O:13]2

Participants

3

Reactant 2

HCID 177502122-Aminopyrimidine-5-boronic acid, pinacol esterHCID 582043229-Bromo-2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine

Product 1

HCID 582050225-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)pyrimidin-2-amine

Sources & evidence

ORD record
ord-b995c0aa251a42f9b3902425c1c20ec8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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