Chloroform → 4-((2'-oxo-3,7-dihydro-2H-spiro[benzofuro[5,6-b][1,4]dioxine-8,3'-indoline]-1'-yl)methyl)benzoyl chloride

HRID 815060Notes

Reaction equation

HRID 815060 reaction equation
[CH:37]([Cl:38])([Cl:39])[Cl:40].[O:1]=[C:2]1[N:3]([CH2:23][c:24]2[cH:25][cH:26][c:27]([C:28](=[O:29])[OH:30])[cH:31][cH:32]2)[c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[C:10]12[CH2:11][O:12][c:13]1[cH:14][c:15]3[c:16]([cH:21][c:22]12)[O:17][CH2:18][CH2:19][O:20]3.[S:33]([Cl:34])([Cl:35])=[O:36]>>[O:1]=[C:2]1[N:3]([CH2:23][c:24]2[cH:25][cH:26][c:27]([C:28](=[O:29])[Cl:35])[cH:31][cH:32]2)[c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[C:10]12[CH2:11][O:12][c:13]1[cH:14][c:15]3[c:16]([cH:21][c:22]12)[O:17][CH2:18][CH2:19][O:20]3

Participants

4

Reactant 3

HCID 6212ChloroformHCID 24386Thionyl ChlorideHCID 461947074-[(2'-oxo-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-1'(2'H)-yl)methyl]benzoic acid

Product 1

HCID 866421984-((2'-oxo-3,7-dihydro-2H-spiro[benzofuro[5,6-b][1,4]dioxine-8,3'-indoline]-1'-yl)methyl)benzoyl chloride

Sources & evidence

ORD record
ord-a441533b2ed74e96a913226cfbac879d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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