Potassium Cation → 2-[4'-(3''-Fluoropropoxy)phenyl]-6-iodoimidazo[1,2-a]pyridine

HRID 815184Notes

Reaction equation

HRID 815184 reaction equation
[Br:24][CH2:25][CH2:26][CH2:27][F:28].[C:18](=[O:19])([O-:20])[O-:21].[CH:30]([Cl:31])([Cl:32])[Cl:33].[K+:22].[K+:23].[OH2:29].[OH:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][c:13]([I:16])[cH:14][cH:15]3)[cH:17]2)[cH:6][cH:7]1>>[O:1]([c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][c:13]([I:16])[cH:14][cH:15]3)[cH:17]2)[cH:6][cH:7]1)[CH2:25][CH2:26][CH2:27][F:28]

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6212ChloroformHCID 19660Carbonate IonHCID 67699Propane, 1-bromo-3-fluoro-HCID 247570112-(4'-Hydroxyphenyl)-6-iodoimidazo[1,2-a]pyridine

Product 1

HCID 247569272-[4'-(3''-Fluoropropoxy)phenyl]-6-iodoimidazo[1,2-a]pyridine

Sources & evidence

ORD record
ord-7655f15629c74c00a9384e073eeac731
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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