Methanol → 8-Chloro-7-fluoro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Reaction equation
[CH3:23][OH:24].[F:1][C:2]([F:3])([F:4])[C:19]([N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:13][c:14]([Cl:18])[c:15]([F:17])[cH:16]2)[CH:10]([CH3:12])[CH2:11]1)=[O:20].[Na+:22].[OH-:21]>>[NH:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:13][c:14]([Cl:18])[c:15]([F:17])[cH:16]2)[CH:10]([CH3:12])[CH2:11]1Participants
5
Sources & evidence
- ORD record
- ord-ff306008f70c4eb4a1cc87a9ef8fcae4
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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