Acetone → 4-(2-Chloro-5-isothiocyanatophenyl)-3-fluoropyridine

HRID 815362Notes

Reaction equation

HRID 815362 reaction equation
[C:16](=[O:17])([OH:18])[O-:19].[CH3:25][C:26](=[O:27])[CH3:28].[Cl:1][c:2]1[c:3](-[c:9]2[c:10]([F:15])[cH:11][n:12][cH:13][cH:14]2)[cH:4][c:5]([NH2:8])[cH:6][cH:7]1.[Cl:21][C:22]([Cl:23])=[S:24].[Na+:20]>>[Cl:1][c:2]1[c:3](-[c:9]2[c:10]([F:15])[cH:11][n:12][cH:13][cH:14]2)[cH:4][c:5]([N:8]=[C:22]=[S:24])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 769Bicarbonate IonHCID 923Sodium ionHCID 10040ThiophosgeneHCID 690046574-Chloro-3-(3-fluoropyridin-4-yl)benzenamine

Product 1

HCID 860453294-(2-Chloro-5-isothiocyanatophenyl)-3-fluoropyridine

Sources & evidence

ORD record
ord-a5b8225b99b2404bb296fef10c377fde
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…