Potassium Cation → Tert-butyl 4-(2-(1,3-dioxoisoindolin-2-YL)ethyl)piperazine-1-carboxylate

HRID 815461Notes

Reaction equation

HRID 815461 reaction equation
[Br:14][CH2:15][CH2:16][N:17]1[C:18](=[O:27])[c:19]2[c:20]([cH:23][cH:24][cH:25][cH:26]2)[C:21]1=[O:22].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[C:28](=[O:29])([O-:30])[O-:31].[CH3:36][C:37]([CH2:38][CH3:39])=[O:40].[I-:35].[K+:32].[K+:33].[Na+:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:15][CH2:16][N:17]2[C:18](=[O:27])[c:19]3[c:20]([cH:23][cH:24][cH:25][cH:26]3)[C:21]2=[O:22])[CH2:12][CH2:13]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 923Sodium ionHCID 6569Methyl Ethyl KetoneHCID 113251H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)-HCID 19660Carbonate IonHCID 30165Iodide IonHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 22397705Tert-butyl 4-(2-(1,3-dioxoisoindolin-2-YL)ethyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-af7588f8d5c14fb9830da71902b9c979
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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