Tetrahydrofuran → 6-[2-(1H-1-imidazolyl)ethoxy]-7-methyl-1,2,3,4-tetrahydro-1-naphthalenone

HRID 815658Notes

Reaction equation

HRID 815658 reaction equation
[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:58][CH2:59][O:60][C:61]([CH3:62])=[O:63].[O:41]=[C:42]([O:43][CH2:44][CH3:45])[N:46]=[N:47][C:48]([O:49][CH2:50][CH3:51])=[O:52].[OH:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][c:11]1[CH3:12])[C:8](=[O:13])[CH2:7][CH2:6][CH2:5]2.[c:22]1([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1.[n:14]1([CH2:19][CH2:20][OH:21])[cH:15][n:16][cH:17][cH:18]1>>[O:1]([c:2]1[cH:3][c:4]2[c:9]([cH:10][c:11]1[CH3:12])[C:8](=[O:13])[CH2:7][CH2:6][CH2:5]2)[CH2:20][CH2:19][n:14]1[cH:15][n:16][cH:17][cH:18]1

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 11776TriphenylphosphineHCID 74168N-(2-Hydroxyethyl)imidazoleHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 186264826-Hydroxy-7-methyl-1,2,3,4-tetrahydronaphthalen-1-one

Product 1

HCID 186265056-[2-(1H-1-imidazolyl)ethoxy]-7-methyl-1,2,3,4-tetrahydro-1-naphthalenone

Sources & evidence

ORD record
ord-ec652f99cf504a8898e637cfdc033e7e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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