O-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]hydroxylamine → 5-(4-bromo-2-fluoroanilino)-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]imidazo[1,5-a]pyrazine-6-carboxamide

HRID 815785Notes

Reaction equation

HRID 815785 reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:27])[c:5]([NH:8][c:9]2[c:10]([C:18](=[O:19])[NH:20][O:21][CH2:22][CH2:23][O:24][CH:25]=[CH2:26])[n:11][cH:12][c:13]3[n:14]2[cH:15][n:16][cH:17]3)[cH:6][cH:7]1.[CH3:28][C:29]1([CH3:37])[O:30][CH2:31][CH:32]([CH2:34][O:35][NH2:36])[O:33]1>>[Br:1][c:2]1[cH:3][c:4]([F:27])[c:5]([NH:8][c:9]2[c:10]([C:18](=[O:19])[NH:36][O:35][CH2:34][CH:32]3[CH2:31][O:30][C:29]([CH3:28])([CH3:37])[O:33]3)[n:11][cH:12][c:13]3[n:14]2[cH:15][n:16][cH:17]3)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 10240948O-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]hydroxylamineHCID 591401825-(4-Bromo-2-fluorophenylamino)-N-(2-(vinyloxy)ethoxy)-imidazo[1,5-a]pyrazine-6-carboxamide

Product 1

HCID 725268885-(4-bromo-2-fluoroanilino)-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]imidazo[1,5-a]pyrazine-6-carboxamide

Sources & evidence

ORD record
ord-2f8fa0a594cf4561b8eefdd0b262fc43
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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