Acetonitrile → Trans-1-(4-Chloro-phenyl)-3-(4-{2-[4-(2,4-difluoro-benzoyl)-piperidin-1-yl]-ethyl}-cyclohexyl)-urea
Reaction equation
[CH3:36][C:37]#[N:38].[Cl:26][c:27]1[cH:28][cH:29][c:30]([N:33]=[C:34]=[O:35])[cH:31][cH:32]1.[NH2:1][CH:2]1[CH2:3][CH2:4][CH:5]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH:13]([C:16](=[O:17])[c:18]3[c:19]([F:25])[cH:20][c:21]([F:24])[cH:22][cH:23]3)[CH2:14][CH2:15]2)[CH2:6][CH2:7]1>>[NH:1]([CH:2]1[CH2:3][CH2:4][CH:5]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH:13]([C:16](=[O:17])[c:18]3[c:19]([F:25])[cH:20][c:21]([F:24])[cH:22][cH:23]3)[CH2:14][CH2:15]2)[CH2:6][CH2:7]1)[C:34]([NH:33][c:30]1[cH:29][cH:28][c:27]([Cl:26])[cH:32][cH:31]1)=[O:35]Participants
4
Sources & evidence
- ORD record
- ord-863b4ec55bed444c8cc09c0594738f4a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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