3-Ethoxy-4-fluorobenzaldehyde → N-[1-(3-Ethoxy-4-fluoro-benzyl)piperidin-4-yl]-5-methyl-nicotinamide
Reaction equation
[CH2:17]([CH3:18])[O:19][c:20]1[cH:21][c:22]([CH:23]=[O:24])[cH:25][cH:26][c:27]1[F:28].[CH3:1][c:2]1[cH:3][n:4][cH:5][c:6]([C:7](=[O:8])[NH:9][CH:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)[cH:16]1>>[CH3:1][c:2]1[cH:3][n:4][cH:5][c:6]([C:7](=[O:8])[NH:9][CH:10]2[CH2:11][CH2:12][N:13]([CH2:23][c:22]3[cH:21][c:20]([O:19][CH2:17][CH3:18])[c:27]([F:28])[cH:26][cH:25]3)[CH2:14][CH2:15]2)[cH:16]1Participants
3
Sources & evidence
- ORD record
- ord-86500684e7654c0d969168cff19e5ff8
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…