3-(Trifluoromethyl)piperidine → 6-(2-Pentynyloxy)-4-(3-trifluoromethylpiperidino)pyrimidine
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]([O:8][CH2:9][C:10]#[C:11][CH2:12][CH3:13])[cH:7]1.[F:14][C:15]([CH:16]1[CH2:17][NH:18][CH2:19][CH2:20][CH2:21]1)([F:22])[F:23]>>[c:2]1([N:18]2[CH2:17][CH:16]([C:15]([F:14])([F:22])[F:23])[CH2:21][CH2:20][CH2:19]2)[n:3][cH:4][n:5][c:6]([O:8][CH2:9][C:10]#[C:11][CH2:12][CH3:13])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-9e55ab1f412b4bc0b6aaa89a08266819
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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