Diethyl (2-amino-2-oxoethyl)phosphonate → N-cyclopropyl-2-(7-fluoro-3,4-dihydro-2H-naphthalen-1-ylidene)acetamide

HRID 816507Notes

Reaction equation

HRID 816507 reaction equation
[C:1]([CH2:2][P:3](=[O:4])([O:5][CH2:6][CH3:7])[O:8][CH2:9][CH3:10])(=[O:11])[NH2:12].[CH2:25]([O:26][P:27](=[O:28])([O:29][CH2:30][CH3:31])[CH2:33][C:34]([NH:35][CH:36]1[CH2:37][CH2:38]1)=[O:39])[CH3:32].[F:13][c:14]1[cH:15][cH:16][c:17]2[c:22]([cH:23]1)[C:21](=[O:24])[CH2:20][CH2:19][CH2:18]2>>[F:13][c:14]1[cH:15][cH:16][c:17]2[c:22]([cH:23]1)[C:21](=[CH:33][C:34]([NH:35][CH:36]1[CH2:37][CH2:38]1)=[O:39])[CH2:20][CH2:19][CH2:18]2

Participants

4

Reactant 3

HCID 225722Diethyl (2-amino-2-oxoethyl)phosphonateHCID 103747647-Fluoro-1,2,3,4-tetrahydronaphthalen-1-oneHCID 54270018Diethyl [2-(cyclopropylamino)-2-oxoethyl]phosphonate

Product 1

HCID 54247618N-cyclopropyl-2-(7-fluoro-3,4-dihydro-2H-naphthalen-1-ylidene)acetamide

Sources & evidence

ORD record
ord-abdaf15b83b5427ca2125fc4bc9e3d65
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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