HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → 6-({5-[2-(isopropylamino)ethoxy]pyridin-2-yl}oxy)-N-(5-methylpyrazin-2-yl)quinazoline-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 5-(2,2-Diethoxyethoxy)-2-fluoropyridine | HCID 68429706 | — |
| Reactant | 4-((5-Methylpyrazin-2-yl)amino)quinazolin-6-ol | HCID 135618222 | — |
| Product | 6-({5-[2-(isopropylamino)ethoxy]pyridin-2-yl}oxy)-N-(5-methylpyrazin-2-yl)quinazoline-4-amine | HCID 59508859 | — |
Reaction Steps
Using 4-[(5-methylpyrazin-2-yl)amino]quinazolin-6-ol, 5-(2,2-diethoxyethoxy)-2-fluoropyridine and isopropylamine, and in the same manner as in Example 31 or according to a method similar to it or according to a combination thereof with an ordinary method, the entitled compound (62 mg) was obtained as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846700B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-34ecc08e5aa84568b9e3fab9a9c5c72a |
| Source note | uspto-grants-2014_09 |