Acetate → Ethyl 3-[6-[(1-benzylpyrrolidin-3-yl)amino]-3-pyridinyl]prop-2-enoate

HRID 816532Notes

Reaction equation

HRID 816532 reaction equation
[C:15](=[O:16])([O-:17])[O-:18].[CH2:21]([c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[N:28]1[CH2:29][CH:30]([NH2:33])[CH2:31][CH2:32]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]=[CH:9][C:10](=[O:11])[O:12][CH2:13][CH3:14])[cH:6][n:7]1.[Cs+:19].[Cs+:20].[O-:41][C:42]([CH3:43])=[O:44].[O-:45][C:46]([CH3:47])=[O:48].[O:34]1[CH2:35][CH2:36][O:37][CH2:38][CH2:39]1.[Pd+2:40]>>[c:2]1([NH:33][CH:30]2[CH2:29][N:28]([CH2:21][c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[CH2:32][CH2:31]2)[cH:3][cH:4][c:5]([CH:8]=[CH:9][C:10](=[O:11])[O:12][CH2:13][CH3:14])[cH:6][n:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 27566131-Benzyl-3-aminopyrrolidineHCID 53406713(E)-Ethyl 3-(6-chloropyridin-3-YL)acrylate

Product 1

HCID 91254562Ethyl 3-[6-[(1-benzylpyrrolidin-3-yl)amino]-3-pyridinyl]prop-2-enoate

Sources & evidence

ORD record
ord-8c655b8b549d4d9582fd2db4beaf2d45
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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