2,4-Dichloro-5-fluoropyrimidine → 2-chloro-N4-[3-(2-ethoxycarbonylmethylene-1,3,4-oxadiazol-5-yl)phenyl]-5-fluoro-4-pyrimidineamine
Reaction equation
[CH2:10]([CH3:11])[O:12][C:13](=[O:14])[CH:15]=[C:16]1[O:17][C:18]([c:21]2[cH:22][c:23]([NH2:24])[cH:25][cH:26][cH:27]2)=[N:19][NH:20]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:24][c:23]2[cH:22][c:21]([C:18]3=[N:19][NH:20][C:16](=[CH:15][C:13]([O:12][CH2:10][CH3:11])=[O:14])[O:17]3)[cH:27][cH:26][cH:25]2)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-9a4b94e589de47299f516094dc5824d8
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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