Dimethyl Sulfoxide → 5-Bromo-1,3-dimethoxyisoquinoline

HRID 816616Notes

Reaction equation

HRID 816616 reaction equation
[Br:1][c:2]1[c:3]2[cH:4][c:5]([Cl:14])[n:6][c:7]([O:12][CH3:13])[c:8]2[cH:9][cH:10][cH:11]1.[CH3:15][O-:16].[CH3:19][S:20]([CH3:21])=[O:22].[Na+:17].[OH2:18]>>[Br:1][c:2]1[c:3]2[cH:4][c:5]([O:16][CH3:15])[n:6][c:7]([O:12][CH3:13])[c:8]2[cH:9][cH:10][cH:11]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 923Sodium ionHCID 962WaterHCID 3826051MethoxideHCID 583494645-Bromo-3-chloro-1-methoxyisoquinoline

Product 1

HCID 673101605-Bromo-1,3-dimethoxyisoquinoline

Sources & evidence

ORD record
ord-65467f3ddc794458804547ae2eb44082
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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