2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetic acid → N-(4-Cyano-3-(1H-1,2,3-triazol-1-yl)thiophen-2-yl)-2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetamide
Reaction equation
[NH2:20][c:21]1[c:22](-[n:28]2[n:29][n:30][cH:31][cH:32]2)[c:23]([C:26]#[N:27])[cH:24][s:25]1.[O:1]=[c:2]1[n:3]([CH2:16][C:17](=[O:18])[OH:19])[c:4]2[cH:5][cH:6][c:7]([C:12]([F:13])([F:14])[F:15])[cH:8][c:9]2[cH:10][cH:11]1>>[O:1]=[c:2]1[n:3]([CH2:16][C:17](=[O:19])[NH:20][c:21]2[c:22](-[n:28]3[n:29][n:30][cH:31][cH:32]3)[c:23]([C:26]#[N:27])[cH:24][s:25]2)[c:4]2[cH:5][cH:6][c:7]([C:12]([F:13])([F:14])[F:15])[cH:8][c:9]2[cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-2b0817a8533e4d96985148a083a844d5
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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