3-Acetamidopyrrolidine → Ethyl 3-[6-(3-acetylamino-1-pyrrolidinyl)-2-chloro-5-fluoropyridin-3-yl]-3-oxopropionate
Reaction equation
[C:18]([CH3:19])(=[O:20])[NH:21][CH:22]1[CH2:23][NH:24][CH2:25][CH2:26]1.[Cl:1][c:2]1[n:3][c:4]([Cl:17])[c:5]([F:16])[cH:6][c:7]1[C:8]([CH2:9][C:10](=[O:11])[O:12][CH2:13][CH3:14])=[O:15]>>[Cl:1][c:2]1[n:3][c:4]([N:24]2[CH2:23][CH:22]([NH:21][C:18]([CH3:19])=[O:20])[CH2:26][CH2:25]2)[c:5]([F:16])[cH:6][c:7]1[C:8]([CH2:9][C:10](=[O:11])[O:12][CH2:13][CH3:14])=[O:15]Participants
3
Sources & evidence
- ORD record
- ord-331e60837417497bbaa0f92aaac8b275
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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