HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(1-Methyl-1H-pyrazol-3-yl)amino]quinazolin-6-ol → 5-chloro-N-[3-(dimethylamino)propyl]-N-methyl-6-({4-[(1-methyl-1H-pyrazol-3-yl)amino]quinazolin-6-yl}oxy)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(1-Methyl-1H-pyrazol-3-yl)amino]quinazolin-6-ol | HCID 23160382 | — |
| Reactant | 5,6-dichloro-N-[3-(dimethylamino)propyl]-N-methylnicotinamide | HCID 63695366 | — |
| Product | 5-chloro-N-[3-(dimethylamino)propyl]-N-methyl-6-({4-[(1-methyl-1H-pyrazol-3-yl)amino]quinazolin-6-yl}oxy)nicotinamide | HCID 42611035 | — |
Reaction Steps
Using 4-[(1-methyl-1H-pyrazol-3-yl)amino]quinazolin-6-ol and 5,6-dichloro-N-[3-(dimethylamino)propyl]-N-methylnicotinamide, and in the same manner as in Example 65 or according to a method similar to it or according to a combination thereof with an ordinary method, the entitled compound (58 mg) was obtained as a yellow amorphous solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846700B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-09bbdaa1315c4ddc9a4772e2903b026d |
| Source note | uspto-grants-2014_09 |