Dimethyl Sulfoxide → 4-[2-Cyano-6-(3-trifluoromethyl-phenyl)-pyrimidin-4-yl]-[1,4]diazepane-1-carboxylic acid tert-butyl ester

HRID 816875Notes

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:15]2[n:16][c:17]([S:31]([CH3:32])(=[O:33])=[O:34])[n:18][c:19](-[c:21]3[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]3)[cH:20]2)[CH2:12][CH2:13][CH2:14]1.[CH3:38][S:39]([CH3:40])=[O:41].[Cl:42][CH2:43][Cl:44].[Na:35][C:36]#[N:37]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:15]2[n:16][c:17]([C:36]#[N:37])[n:18][c:19](-[c:21]3[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]3)[cH:20]2)[CH2:12][CH2:13][CH2:14]1