Formaldehyde → 4-(1-Methylpiperidine-2-carbonyl)piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][N:13]([C:16](=[O:17])[CH:18]2[NH:19][CH2:20][CH2:21][CH2:22][CH2:23]2)[CH2:14][CH2:15]1.[CH2:1]=[O:2].[Cl:24][CH2:25][Cl:26]>>[CH3:1][N:19]1[CH:18]([C:16]([N:13]2[CH2:12][CH2:11][N:10]([C:8]([O:7][C:3]([CH3:4])([CH3:5])[CH3:6])=[O:9])[CH2:15][CH2:14]2)=[O:17])[CH2:23][CH2:22][CH2:21][CH2:20]1Participants
4
Sources & evidence
- ORD record
- ord-f1d136db1e9544b594fe143265fcb0d1
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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