Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 817019Generated: October 30, 2026

Benzene → 4-([3-(tert-butyldimethylsilanyloxy)phenyl]{3-[N-(3-fluorophenyl)-N-methylcarbamoyl]phenyl}-methylene)piperidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/817019

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneHCID 241—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
Reactantp-Toluenesulfonic acidHCID 6101—
ReactantCarbonate IonHCID 19660—
Reactant4-([3-(tert-butyldimethylsilanyloxy)phenyl]{3-[N-(3-fluorophenyl)-N-methyl-carbamoyl]phenyl}hydroxymethyl)piperidine-1-carboxylic acid tert-butyl esterHCID 69790890—
Product4-([3-(tert-butyldimethylsilanyloxy)phenyl]{3-[N-(3-fluorophenyl)-N-methylcarbamoyl]phenyl}-methylene)piperidine-1-carboxylic acid tert-butyl esterHCID 69914374—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-6e7a8823e63c4ddd93d723fe05bb138e
Source noteTest data from https://doi.org/10.1039/C8SC04228D