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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 817048Generated: October 26, 2026

Hydrogen Bromide → 4-(2-Bromoacetyl)-1-[4-[(3-fluorophenyl)methoxy]phenyl]pyrrolidin-2-one

https://huagongshe.com/reaction/817048

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantHexaneHCID 8058—
ReactantEthyl AcetateHCID 8857—
ReactantThionyl ChlorideHCID 24386—
ReactantTrimethylsilyldiazomethaneHCID 167693—
ReactantRac-1-[4-(3-fluoro-benzyloxy)-phenyl]-5-oxo-pyrrolidine-3-carboxylic acidHCID 21920015—
Product4-(2-Bromoacetyl)-1-[4-[(3-fluorophenyl)methoxy]phenyl]pyrrolidin-2-oneHCID 87780446—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-0cf1ff0fa3fd45e6a1c25ce8840e59ea
Source noteTest data from https://doi.org/10.1039/C8SC04228D