HuagongsheHuagongshe Chemistry Print Report · For research reference only
M-Phenylenediamine → N1-(4-(pyridin-2-ylthio)pyrimidin-2-yl)benzene-1,3-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | M-Phenylenediamine | HCID 7935 | — |
| Reactant | 2-Chloro-4-(pyridin-2-ylthio)pyrimidine | HCID 62341899 | — |
| Product | N1-(4-(pyridin-2-ylthio)pyrimidin-2-yl)benzene-1,3-diamine | HCID 68749996 | 30.1% |
Reaction Steps
In a procedure analogous to Example 6, reaction of 2-chloro-4-(pyridin-2-ylthio)pyrimidine (100 mg, 0.45 mmol) and 1,3-phenylenediamine (193 mg, 1.78 mmol) furnished the product (40 mg, 30%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846704B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-2e164a36f5334bf1959405f5f75148fb |
| Source note | uspto-grants-2014_09 |