HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylic Acid → N-(3-(2-chloropyrimidin-4-ylthio)phenyl)acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylic Acid | HCID 6581 | — |
| Reactant | 3-(2-Chloropyrimidin-4-ylthio)benzenamine | HCID 86645573 | — |
| Product | N-(3-(2-chloropyrimidin-4-ylthio)phenyl)acrylamide | HCID 86645569 | 68% |
Reaction Steps
In a procedure analogous to Example 15, reaction of 3-(2-chloropyrimidin-4-ylthio)benzenamine (300 mg, 1.26 mmol) and acrylic acid (173 μL, 2.52 mmol) furnished the product (250 mg, 68%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846704B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-8b1771262c5e44ada19659657c7eb43e |
| Source note | uspto-grants-2014_09 |