1-(2,3-Dihydro-1H-inden-4-yl)piperazine → 6-Fluoro-7-[4-(4-indan-4-yl-piperazin-1-yl)-butoxy]-3,4-dihydro-1H-[1,8]naphthyridin-2-one
Reaction equation
[CH2:19]1[CH2:20][CH2:21][c:22]2[c:23]([N:28]3[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]3)[cH:24][cH:25][cH:26][c:27]21.[F:1][c:2]1[c:3]([O:13][CH2:14][CH2:15][CH2:16][CH:17]=[O:18])[n:4][c:5]2[c:10]([cH:11]1)[CH2:9][CH2:8][C:7](=[O:12])[NH:6]2>>[F:1][c:2]1[c:3]([O:13][CH2:14][CH2:15][CH2:16][CH2:17][N:31]2[CH2:30][CH2:29][N:28]([c:23]3[c:22]4[c:27]([cH:26][cH:25][cH:24]3)[CH2:19][CH2:20][CH2:21]4)[CH2:33][CH2:32]2)[n:4][c:5]2[c:10]([cH:11]1)[CH2:9][CH2:8][C:7](=[O:12])[NH:6]2Participants
3
Sources & evidence
- ORD record
- ord-4ff61d8a9a3f42519bb899eda9c46f71
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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