Carbamic acid,[2-amino-4-chloro-5-[(2-methylpropyl)amino]phenyl]-,1,1-dimethylethyl ester → {4-Chloro-2-[3-(3-imidazol-1-yl-phenyl)-3-oxo-propionylamino]-5-isobutylamino-phenyl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:20])[cH:10][c:11]([Cl:19])[c:12]([NH:14][CH2:15][CH:16]([CH3:17])[CH3:18])[cH:13]1)=[O:21].[C:22]([CH3:24])([CH3:25])([O:26][C:27](=[O:23])[CH2:28][C:29](=[O:30])[c:31]1[cH:32][c:33](-[n:37]2[cH:38][n:39][cH:40][cH:41]2)[cH:34][cH:35][cH:36]1)[CH3:42]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:20][C:27](=[O:26])[CH2:28][C:29](=[O:30])[c:31]2[cH:32][c:33](-[n:37]3[cH:38][n:39][cH:40][cH:41]3)[cH:34][cH:35][cH:36]2)[cH:10][c:11]([Cl:19])[c:12]([NH:14][CH2:15][CH:16]([CH3:17])[CH3:18])[cH:13]1)=[O:21]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5bb5d7ba76404551ab2cb6c70d11ed04
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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