4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholine → 1-(2-Chloro-3,6-difluorobenzyl)-7-(3-morpholin-4-yl-phenyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine
Reaction equation
[CH3:28][C:29]1([CH3:30])[C:31]([CH3:32])([CH3:33])[O:34][B:35]([c:36]2[cH:37][c:38]([N:42]3[CH2:43][CH2:44][O:45][CH2:46][CH2:47]3)[cH:39][cH:40][cH:41]2)[O:48]1.[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:11][cH:12][c:13](-[c:15]4[cH:16][cH:17][n:18][c:19]([Cl:20])[cH:21]4)[cH:14]3)[NH:8][CH2:9][CH2:10]2)[c:22]([F:27])[cH:23][cH:24][c:25]1[F:26]>>[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:11][cH:12][c:13](-[c:36]4[cH:37][c:38]([N:42]5[CH2:43][CH2:44][O:45][CH2:46][CH2:47]5)[cH:39][cH:40][cH:41]4)[cH:14]3)[NH:8][CH2:9][CH2:10]2)[c:22]([F:27])[cH:23][cH:24][c:25]1[F:26]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-1cb041326e724d1fae6fe9f9c18a8a85
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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