Pyridine → 1,1-Dimethylethyl 4-(5-(2-chloro-4-pyrimidinyl)-4-{2-fluoro-3-[(3-furanylsulfonyl)amino]phenyl}-1,3-thiazol-2-yl)-4-methyl-1-piperidinecarboxylate
Reaction equation
[NH2:1][c:2]1[c:3]([F:34])[c:4](-[c:8]2[n:9][c:10]([C:20]3([CH3:33])[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]3)[s:11][c:12]2-[c:13]2[n:14][c:15]([Cl:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1.[cH:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1.[o:35]1[cH:36][c:37]([S:40](=[O:41])(=[O:42])[Cl:43])[cH:38][cH:39]1>>[NH:1]([c:2]1[c:3]([F:34])[c:4](-[c:8]2[n:9][c:10]([C:20]3([CH3:33])[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]3)[s:11][c:12]2-[c:13]2[n:14][c:15]([Cl:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1)[S:40]([c:37]1[cH:36][o:35][cH:39][cH:38]1)(=[O:41])=[O:42]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-3fdb3e437c3d48a7a2abeded14fa3008
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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