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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 817430Generated: October 30, 2026

Diisopropylamine → 3,5-difluoro-4-[1-hydroxy-3-(1-trityl-1H-imidazol-4-yl)-propyl]benzonitrile

https://huagongshe.com/reaction/817430

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylamineHCID 7912—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
Reactant3,5-DifluorobenzonitrileHCID 587204—
Reactant3-(1-Tritylimidazol-4-YL) propionaldehydeHCID 11451428—
ReactantButyllithiumHCID 178418339—
Product3,5-difluoro-4-[1-hydroxy-3-(1-trityl-1H-imidazol-4-yl)-propyl]benzonitrileHCID 66885515—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-565680b14fb74afb8c50243c1576244e
Source noteTest data from https://doi.org/10.1039/C8SC04228D