Benzene → 3,4-Dichloro-N-[[1-(4-methyl-1-piperazinyl)cyclohexyl]methyl]-benzamide
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[Cl:7])[cH:8][cH:9][c:10]1[Cl:11].[NH2:12][CH2:13][C:14]1([N:20]2[CH2:21][CH2:22][N:23]([CH3:26])[CH2:24][CH2:25]2)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1.[OH2:33].[cH:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:12][CH2:13][C:14]2([N:20]3[CH2:21][CH2:22][N:23]([CH3:26])[CH2:24][CH2:25]3)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]2)[cH:8][cH:9][c:10]1[Cl:11]Participants
5
Sources & evidence
- ORD record
- ord-677f5c5537fa4e309d9cdce008e6329f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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