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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 817561Generated: October 30, 2026

Dichloromethane → 8-Chloro-7-dimethylamino-4-[3-(3-methyl-isoxazol-5-yl)-phenyl]-1,3-dihydro-benzo[b][1,4]diazepin-2-one

https://huagongshe.com/reaction/817561

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant(4-Chloro-5-dimethylamino-2-{3-[3-(3-methyl-isoxazol-5-yl)-phenyl]-3-oxo-propionylamino}-phenyl)-carbamic acid tert.-butyl esterHCID 86586804—
Product8-Chloro-7-dimethylamino-4-[3-(3-methyl-isoxazol-5-yl)-phenyl]-1,3-dihydro-benzo[b][1,4]diazepin-2-oneHCID 18613469—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-eff68591c17a4a23adcc4ab812e06f9e
Source noteTest data from https://doi.org/10.1039/C8SC04228D