3-Oxo-3-(3-[1,2,3)triazol-1-yl-phenyl)-propionic acid ethyl ester → {2-Dimethylamino-2',3'-difluoro-5-[3-oxo-3-(3-[1,2,3]triazol-1-yl-phenyl)-propionylamino]-biphenyl-4-yl}-carbamic acid tert.-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[cH:9][c:10]([N:23]([CH3:24])[CH3:25])[c:11](-[c:15]2[c:16]([F:22])[c:17]([F:21])[cH:18][cH:19][cH:20]2)[cH:12][c:13]1[NH2:14])=[O:26].[CH2:27]([O:29][C:30](=[O:28])[CH2:31][C:32]([c:33]1[cH:34][c:35](-[n:39]2[n:40][n:41][cH:42][cH:43]2)[cH:36][cH:37][cH:38]1)=[O:44])[CH3:45]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[cH:9][c:10]([N:23]([CH3:24])[CH3:25])[c:11](-[c:15]2[c:16]([F:22])[c:17]([F:21])[cH:18][cH:19][cH:20]2)[cH:12][c:13]1[NH:14][C:30](=[O:29])[CH2:31][C:32]([c:33]1[cH:34][c:35](-[n:39]2[n:40][n:41][cH:42][cH:43]2)[cH:36][cH:37][cH:38]1)=[O:44])=[O:26]Participants
3
Sources & evidence
- ORD record
- ord-e83fafd204cb4ec8bc4dc4e576d633ae
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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