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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 817865Generated: October 26, 2026

4-Hydroxy-2-hydroxymethyl-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl ester → 4-(4-Dimethylcarbamoyl-3-fluoro-phenoxy)-2-hydroxymethyl-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/817865

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxy-2-hydroxymethyl-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl esterHCID 59559905—
Reactant6-(4-Methanesulfonyl-phenoxy)-2-methyl-2,3-dihydro-benzofuran-4-carboxylic acid methyl esterHCID 59560437—
ReactantHCID 60637230HCID 60637230—
Product4-(4-Dimethylcarbamoyl-3-fluoro-phenoxy)-2-hydroxymethyl-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl esterHCID 59560164—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-7eaa05632ee449e8a545486ae1450c0b
Source noteTest data from https://doi.org/10.1039/C8SC04228D