Methanol → 5-(3,5-Bis-trifluoromethyl-benzylamino)-7-bromo-8-chloro-2,3,4,5-tetrahydro-benzo[b]azepine-1-carboxylic acid isopropyl ester

HRID 817909Notes

Reaction equation

[C:37]([BH3-:38])#[N:39].[CH3:41][OH:42].[CH3:43][CH:44]([CH3:45])[O-:46].[CH3:48][CH:49]([CH3:50])[O-:51].[CH3:52][CH:53]([CH3:54])[O-:55].[CH3:56][CH:57]([CH3:58])[O-:59].[CH:1]([CH3:2])([CH3:3])[O:4][C:5](=[O:6])[N:7]1[c:8]2[c:9]([cH:15][c:16]([Br:20])[c:17]([Cl:19])[cH:18]2)[C:10](=[O:14])[CH2:11][CH2:12][CH2:13]1.[F:21][C:22]([c:23]1[cH:24][c:25]([CH2:26][NH2:27])[cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]1)([F:35])[F:36].[Na+:40].[Ti+4:47]>>[CH:1]([CH3:2])([CH3:3])[O:4][C:5](=[O:6])[N:7]1[c:8]2[c:9]([cH:15][c:16]([Br:20])[c:17]([Cl:19])[cH:18]2)[CH:10]([NH:27][CH2:26][c:25]2[cH:24][c:23]([C:22]([F:21])([F:35])[F:36])[cH:30][c:29]([C:31]([F:32])([F:33])[F:34])[cH:28]2)[CH2:11][CH2:12][CH2:13]1