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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 817930Generated: November 2, 2026

1,2-Dichloroethane → 2-(4-Fluorophenyl)-N-methyl-5-(2-methyl-5-(1-(pyrimidin-2-yl)cyclopropylcarbamoyl)phenyl)benzofuran-3-carboxamide

https://huagongshe.com/reaction/817930

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-(Pyrimidin-2-yl)cyclopropan-1-amineHCID 56965659—
Reactant3-(2-(4-Fluorophenyl)-3-(methylcarbamoyl)benzofuran-5-yl)-4-methylbenzoic acidHCID 59275653—
Product2-(4-Fluorophenyl)-N-methyl-5-(2-methyl-5-(1-(pyrimidin-2-yl)cyclopropylcarbamoyl)phenyl)benzofuran-3-carboxamideHCID 46178246—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-5949e0fcfaa9404c82c244ce2efd9790
Source noteTest data from https://doi.org/10.1039/C8SC04228D