Dichloromethane → 2'-(chloromethyl)spiro[1H-pyrrolo[2,3-b]pyridine-3,7'-6,8-dihydrocyclopenta[g]quinoline]-2-one
Reaction equation
[Cl:29][CH2:30][Cl:31].[OH:1][CH2:2][c:3]1[n:4][c:5]2[cH:6][c:7]3[c:8]([cH:9][c:10]2[cH:11][cH:12]1)[CH2:13][C:14]1([CH2:15]3)[C:16](=[O:24])[NH:17][c:18]2[n:19][cH:20][cH:21][cH:22][c:23]21.[S:25]([Cl:26])([Cl:27])=[O:28]>>[CH2:2]([c:3]1[n:4][c:5]2[cH:6][c:7]3[c:8]([cH:9][c:10]2[cH:11][cH:12]1)[CH2:13][C:14]1([CH2:15]3)[C:16](=[O:24])[NH:17][c:18]2[n:19][cH:20][cH:21][cH:22][c:23]21)[Cl:27]Participants
4
Sources & evidence
- ORD record
- ord-f4d8bfee2634446cbfbacf5d215f632a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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