Tert-butyl (3-amino-4'-fluoro-[1,1'-biphenyl]-4-YL)carbamate → (3-{3-[3-(2,4-Dimethyl-imidazol-1-yl)-phenyl]-3-oxo-propionylamino}-4'-fluoro-biphenyl-4-yl)-carbamic acid tert.-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:21])[cH:10][c:11](-[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[cH:12][cH:13]1)=[O:22].[C:23]([CH3:25])([CH3:26])([O:27][C:28](=[O:24])[CH2:29][C:30](=[O:31])[c:32]1[cH:33][c:34](-[n:38]2[c:39]([CH3:44])[n:40][c:41]([CH3:43])[cH:42]2)[cH:35][cH:36][cH:37]1)[CH3:45]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:21][C:28](=[O:27])[CH2:29][C:30](=[O:31])[c:32]2[cH:33][c:34](-[n:38]3[c:39]([CH3:44])[n:40][c:41]([CH3:43])[cH:42]3)[cH:35][cH:36][cH:37]2)[cH:10][c:11](-[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[cH:12][cH:13]1)=[O:22]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-df3f08ffbf284f34aa89a4686aae8cfd
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…