Potassium Cation → 7-Chloro-10-(methylthio)-4H-thieno[3,4-b] [1,5]benzodiazepine

HRID 818083Notes

Reaction equation

HRID 818083 reaction equation
[CH3:19][O:20][S:21](=[O:22])(=[O:23])[OH:24].[CH3:31][OH:32].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:16]1)[NH:7][C:8](=[S:15])[c:9]1[c:10]([cH:12][s:13][cH:14]1)[NH:11]2.[K+:18].[O:25]1[CH2:26][CH2:27][O:28][CH2:29][CH2:30]1.[OH-:17]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:16]1)[N:7]=[C:8]([S:15][CH3:19])[c:9]1[c:10]([cH:12][s:13][cH:14]1)[NH:11]2

Participants

7

Reactant 6

HCID 813Potassium CationHCID 887MethanolHCID 961HydroxideHCID 6412Monomethyl sulfateHCID 312751,4-DioxaneHCID 125216547-Chloro-4,9-dihydro-10H-thieno[3,4-b][1,5]benzodiazepin-10-thione

Product 1

HCID 125216627-Chloro-10-(methylthio)-4H-thieno[3,4-b] [1,5]benzodiazepine

Sources & evidence

ORD record
ord-08e5c7eed7544920aa7742bf7fcb5983
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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