1,2,2-Trimethylpiperazine → 5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-methyl-1H-indazol-5-yl}methylidene)-2-(3,3,4-trimethylpiperazin-1-yl)-1,3-thiazol-4(5H)-one

HRID 818148Notes

Reaction equation

HRID 818148 reaction equation
[CH3:33][N:34]1[C:35]([CH3:40])([CH3:41])[CH2:36][NH:37][CH2:38][CH2:39]1.[Cl:1][c:2]1[cH:3][c:4]([C:29]([F:30])([F:31])[F:32])[c:5]([CH2:6][n:7]2[n:8][c:9]([CH3:26])[c:10]3[cH:11][c:12]([CH:16]=[C:17]4[C:18](=[O:25])[N:19]=[C:20]([S:22][CH2:23][CH3:24])[S:21]4)[cH:13][cH:14][c:15]23)[cH:27][cH:28]1>>[Cl:1][c:2]1[cH:3][c:4]([C:29]([F:30])([F:31])[F:32])[c:5]([CH2:6][n:7]2[n:8][c:9]([CH3:26])[c:10]3[cH:11][c:12]([CH:16]=[C:17]4[C:18](=[O:25])[N:19]=[C:20]([N:37]5[CH2:36][C:35]([CH3:40])([CH3:41])[N:34]([CH3:33])[CH2:39][CH2:38]5)[S:21]4)[cH:13][cH:14][c:15]23)[cH:27][cH:28]1

Participants

3

Reactant 2

HCID 219737761,2,2-TrimethylpiperazineHCID 672404815-[1-(4-Chloro-2-trifluoromethyl-benzyl)-3-methyl-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one

Product 1

HCID 672404305-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-methyl-1H-indazol-5-yl}methylidene)-2-(3,3,4-trimethylpiperazin-1-yl)-1,3-thiazol-4(5H)-one

Sources & evidence

ORD record
ord-05c43f3cc07843b0b953b9675bd5063e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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