Toluene → (+/-)-Methyl 1'-(4-methoxybenzyl)-2'-oxo-3,4-dihydro-1H-spiro[naphthalene-2,3'-pyrrolidine]-6-carboxylate

HRID 818233Notes

Reaction equation

HRID 818233 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:8][CH2:9][CH2:10][C:11]2([C:25]([O:27][CH3:26])=[O:28])[CH2:12][c:13]3[cH:14][cH:15][c:16]([C:21](=[O:22])[O:23][CH3:24])[cH:17][c:18]3[CH2:19][CH2:20]2)[cH:29][cH:30]1.[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][N:8]2[CH2:9][CH2:10][C:11]3([CH2:12][c:13]4[cH:14][cH:15][c:16]([C:21](=[O:22])[O:23][CH3:24])[cH:17][c:18]4[CH2:19][CH2:20]3)[C:25]2=[O:27])[cH:29][cH:30]1

Participants

3

Reactant 2

HCID 1140TolueneHCID 67525773(+/-)-Dimethyl 2-{2-[(4-methoxybenzyl)amino]ethyl}-1,2,3,4-tetrahydronaphthalene-2,6-dicarboxylate

Product 1

HCID 67526601(+/-)-Methyl 1'-(4-methoxybenzyl)-2'-oxo-3,4-dihydro-1H-spiro[naphthalene-2,3'-pyrrolidine]-6-carboxylate

Sources & evidence

ORD record
ord-2e9ccf96daa44c5ea7b8476b575fc75a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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