4-(2-Chloro-ethanesulfonyl)-phenol → (3SR,4SR)-1-[2-(4-Hydroxy-benzenesulfonyl)-ethyl]-4-(4-methyl-benzyl)-piperidin-3-ol
Reaction equation
[CH3:14][c:15]1[cH:16][cH:17][c:18]([CH2:19][CH:20]2[CH:21]([OH:26])[CH2:22][NH:23][CH2:24][CH2:25]2)[cH:27][cH:28]1.[Cl:1][CH2:2][CH2:3][S:4](=[O:5])(=[O:6])[c:7]1[cH:8][cH:9][c:10]([OH:13])[cH:11][cH:12]1>>[CH2:2]([CH2:3][S:4](=[O:5])(=[O:6])[c:7]1[cH:8][cH:9][c:10]([OH:13])[cH:11][cH:12]1)[N:23]1[CH2:22][CH:21]([OH:26])[CH:20]([CH2:19][c:18]2[cH:17][cH:16][c:15]([CH3:14])[cH:28][cH:27]2)[CH2:25][CH2:24]1Participants
3
Sources & evidence
- ORD record
- ord-22bddce7c2ea417698f69ce52c18e8b6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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