Carbonate Ion → Ethyl 2-[3-(ethylsulfanyl)phenoxy]-5-fluoronicotinate

HRID 818310Notes

Reaction equation

HRID 818310 reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[CH2:14]([CH3:15])[S:16][c:17]1[cH:18][c:19]([OH:23])[cH:20][cH:21][cH:22]1.[Cl:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH2:7][CH3:8])[cH:9][c:10]([F:13])[cH:11][n:12]1.[Cs+:28].[Cs+:29].[O:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1>>[c:2]1([O:23][c:19]2[cH:18][c:17]([S:16][CH2:14][CH3:15])[cH:22][cH:21][cH:20]2)[c:3]([C:4](=[O:5])[O:6][CH2:7][CH3:8])[cH:9][c:10]([F:13])[cH:11][n:12]1

Participants

6

Reactant 5

HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 11390082Ethyl 2-chloro-5-fluoronicotinateHCID 129052213-(Ethylsulfanyl)phenol

Product 1

HCID 21877167Ethyl 2-[3-(ethylsulfanyl)phenoxy]-5-fluoronicotinate

Sources & evidence

ORD record
ord-24d4afcb97f246e5bea7e8530a802ae4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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