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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 818362Generated: October 26, 2026

Hydrochloric Acid → 2-Chloro-5-methoxy-2′-(trifluoromethyl)[1,1′-biphenyl]-4-carboxylic acid

https://huagongshe.com/reaction/818362

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantDimethylformamideHCID 6228—
ReactantTriphenylphosphineHCID 11776—
ReactantCarbonate IonHCID 19660—
ReactantPalladiumHCID 23938—
Reactant2-(Trifluoromethyl)benzeneboronic acidHCID 2734387—
Reactant5-Chloro-4-iodo-2-methoxybenzoic acidHCID 16791858—
Product2-Chloro-5-methoxy-2′-(trifluoromethyl)[1,1′-biphenyl]-4-carboxylic acidHCID 21947754—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d45a350bfe644bc99b463e80cfbce3b8
Source noteTest data from https://doi.org/10.1039/C8SC04228D