2-Morpholino-5-nitrobenzoic acid → (6-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)-(2-morpholin-4-yl-5-nitro-phenyl)-methanone

HRID 818373Notes

Reaction equation

HRID 818373 reaction equation
[Cl:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][NH:7][CH2:6][CH2:5]2.[O:12]1[CH2:13][CH2:14][N:15]([c:18]2[c:19]([C:20](=[O:21])[OH:22])[cH:23][c:24]([N+:27](=[O:28])[O-:29])[cH:25][cH:26]2)[CH2:16][CH2:17]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([C:20]([c:19]1[c:18]([N:15]3[CH2:14][CH2:13][O:12][CH2:17][CH2:16]3)[cH:26][cH:25][c:24]([N+:27](=[O:28])[O-:29])[cH:23]1)=[O:21])[CH2:6][CH2:5]2

Participants

3

Reactant 2

HCID 27257552-Morpholino-5-nitrobenzoic acidHCID 117895946-Chloro-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 57445277(6-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)-(2-morpholin-4-yl-5-nitro-phenyl)-methanone

Sources & evidence

ORD record
ord-dd1f68c0418e47d0a06ef44d3bb81f33
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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