Bromide ion → 1-(4-Amino-3'-chloro-biphenyl-3-yl)-1-cyclopropyl-1-propynyl-methanol

HRID 818391Notes

Reaction equation

HRID 818391 reaction equation
[Br-:20].[C:21](#[C:22][CH3:23])[Mg+:24].[NH2:1][c:2]1[c:3]([C:15](=[O:16])[CH:17]2[CH2:18][CH2:19]2)[cH:4][c:5](-[c:8]2[cH:9][c:10]([Cl:14])[cH:11][cH:12][cH:13]2)[cH:6][cH:7]1>>[NH2:1][c:2]1[c:3]([C:15]([OH:16])([CH:17]2[CH2:18][CH2:19]2)[C:21]#[C:22][CH3:23])[cH:4][c:5](-[c:8]2[cH:9][c:10]([Cl:14])[cH:11][cH:12][cH:13]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 259Bromide ionHCID 23509605(4-Amino-3'-chloro-biphenyl-3-yl)-cyclopropyl-methanoneHCID 178456137HCID 178456137, compound

Product 1

HCID 235096341-(4-Amino-3'-chloro-biphenyl-3-yl)-1-cyclopropyl-1-propynyl-methanol

Sources & evidence

ORD record
ord-8eaa040f509943d3b7b4120435059be8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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