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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 818654Generated: October 31, 2026

Chloride → 8-(2-Chloro-benzenesulfonyl)-2-[2-(4-fluoro-phenyl)-ethyl]-2,8-diaza-spiro[4.5]decan-1-one

https://huagongshe.com/reaction/818654

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantTolueneHCID 1140—
Reactantp-FluorophenethylamineHCID 4653—
ReactantDimethylalumanyliumHCID 16685399—
Reactant1-(2-Chloro-benzenesulfonyl)-4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl esterHCID 66787676—
Product8-(2-Chloro-benzenesulfonyl)-2-[2-(4-fluoro-phenyl)-ethyl]-2,8-diaza-spiro[4.5]decan-1-oneHCID 59577992—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-5af538d1d34f4071a59a2b3f489f7201
Source noteTest data from https://doi.org/10.1039/C8SC04228D