5-bromo-N-(1-hydroxy-2-methylpropan-2-yl)pyridine-3-sulfonamide → 5-[8-Methyl-6-(4-trifluoromethyl-phenyl)-imidazo [1,2-a]pyridin-3-ylethynyl]-pyridine-3-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide
Reaction equation
[C:1](#[CH:2])[c:3]1[cH:4][n:5][c:6]2[n:7]1[cH:8][c:9](-[c:13]1[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]1)[cH:10][c:11]2[CH3:12].[OH:23][CH2:24][C:25]([CH3:26])([CH3:27])[NH:28][S:29](=[O:30])(=[O:31])[c:32]1[cH:33][n:34][cH:35][c:36]([Br:38])[cH:37]1>>[C:1](#[C:2][c:36]1[cH:35][n:34][cH:33][c:32]([S:29]([NH:28][C:25]([CH2:24][OH:23])([CH3:26])[CH3:27])(=[O:30])=[O:31])[cH:37]1)[c:3]1[cH:4][n:5][c:6]2[n:7]1[cH:8][c:9](-[c:13]1[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]1)[cH:10][c:11]2[CH3:12]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-6c1320a8b5394e7396a97c2e88040312
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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