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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 819033Generated: October 27, 2026

Hydrochloric Acid → 7-Fluoro-5-methyl-6-phenyl-2-(piperidin-1-ylcarbonyl)-1,3-benzoxazole-4-carbonitrile

https://huagongshe.com/reaction/819033

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantPiperidineHCID 8082—
ReactantTrimethylaluminumHCID 16682925—
ReactantEthyl 4-cyano-7-fluoro-5-methyl-6-phenyl-1,3-benzoxazole-2-carboxylateHCID 51041426—
Product7-Fluoro-5-methyl-6-phenyl-2-(piperidin-1-ylcarbonyl)-1,3-benzoxazole-4-carbonitrileHCID 68585060—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-b5ee5f62b4da4e1ba9395c01c6ba101a
Source noteTest data from https://doi.org/10.1039/C8SC04228D